From: The dark side of ID8-Luc2: pitfalls for luciferase tagged murine models for ovarian cancer
Criteria of euthanasia | Liao et al. | Improved criteria |
---|---|---|
Weight | Cachexia | Loss of 2 g in 48 h |
Loss of 3 g in 7 days | ||
Clinical deterioration | Increased respiratory frequency | Increased respiratory frequency |
Anorexia | Hunched back with tremor | |
Ascites | / | |
/ | No spontaneous movement when nudged |