Fig. 11 (abstract P211).

USP6 Synergizes with IFN to Massively Upregulate TRAIL. RD-ES were treated with 1000 U/mL IFNa, IFNB, or IFNy for 24 hours with or without USP6 expression. TRAIL was found to be synergistically induced by IFN in the presence of USP6. IFNB was the most potent at nearl5 5000-fold over baseline