Fig. 13 (abstract P211).

USP6 Induces an IFN-Response In Vitro. RNA-sequencing was performed on RD-ES/USP6(Pooled) were treated with or without dox. The resulting gene expression data was analyzed using Gene Sequencing Enrichment Analysis (GSEA) using the Hallmark dataset (the hallmark dataset contains curated gene sets that are known to be part of key cellular pathways). USP6 induces a strong IFN-response and Jak-STAT gene expression