Fig. 33 (abstract P295).

THU-Dec directly cytoreduced lung cancer in vivo by p53-independent mechanisms while preserving immune-effectors and increasing antigen presentation. C57/BL6 mice were inoculated via tail vein with LL3 lung cancer cells. a Survival time; b Protein expression in tumor; c Absolute numbers of CD4/8 T cells in peripheral blood after 2 weeks of treatment; d Absolute numbers of MDSC in blood after 2 weeks of treatment; e Cancer testis antigen expression in tumor; f Intracellular IFNγ expression in tumor. Data were expression as mean ±SD. *p < 0.05, **p < 0.01 vs PBS group