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Fig. 8 (abstract P211). | Journal for ImmunoTherapy of Cancer

Fig. 8 (abstract P211).

From: 31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part two

Fig. 8 (abstract P211).

USP6 Expression in RD-ES Cell Line. USP6 was expressed in a doxycycline-inducible in the patient derived Ewing sarcoma cell line. Clonal lines that express high or medium amounts of USP6 were isolated from the initial pooled population. Expression of USP6 increased Jak1 levels and activation of downstream effectors STAT1 and STAT3 in an USP6 dose dependent manner. Note: Similar lines were/are being created for other sarcomas. RD-ES is used as an example

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