| CRC (IT injection, n = 5) | CRC, NSCLC, UCC, RCC (IV infusion, n = 12) |
---|---|---|
Any AE, n (%)a | 5 (100.0) | 12 (100.0)b |
Treatment-related AE, n (%) | 0 (0) | 10 (83.3) |
 Astheniaa | 0 | 4 |
 Chills | 0 | 3 |
 Neutropenia | 0 | 3 |
 Pyrexia | 0 | 3 |
Any SAE, n (%) | 1 (20.0) | 3 (25.0) |
 Abdominal abscess | 1 | 0 |
 Enteritis | 0 | 1 |
 Subcutaneous emphysema | 0 | 1 |
 Wound dehiscence | 0 | 1 |
Treatment-related SAE | 0 (0.0) | 0 (0.0) |
Any grade 3 or 4 AEs, n (%) | 2 (40.0) | 3 (25.0) |
 Abdominal abscess | 1 | 0 |
 Anemia | 2 | 0 |
 Asthenia | 0 | 1 |
 Enteritis | 0 | 1 |
 Gastrointestinal hemorrhage | 1 | 0 |
 Hypertension | 0 | 1 |
 Hypocalcemia | 1 | 0 |
 Hypokalemia | 1 | 0 |
 Oliguria | 0 | 1 |
 Wound dehiscence | 0 | 1 |
Treatment-related grade 3 or 4 AEs, n (%) | 0 (0.0) | 0 (0.0) |
AE leading to study discontinuation, n (%) | 0 (0.0) | 1 (8.3) |
 Stoma site infection | 0 | 1 |