Volume 3 Supplement 2

30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015)

Meeting abstracts

Publication of this supplement was funded by SITC 2015.

30th Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2015).

National Harbor, MD, USA

4-8 November 2015

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  1. Oral presentation

    A bispecific chimeric antigen receptor molecule enhances T cell activation through dual immunological synapse formation and offsets antigen escape in glioblastoma

    Meenakshi Hegde, Zakaria Grada, Antonella Pignata, Amanda Wakefield, Kristen Fousek, Kevin Bielamowicz, Kevin Chow, Vita Brawley, Tiara Byrd, Stephen Gottschalk, Malini Mukherjee, Winfried S Wels, Matthew Baker, Giapietro Dotti, Jordan Orange and Nabil Ahmed

    Journal for ImmunoTherapy of Cancer 2015 3(Suppl 2):O3

    Published on: 4 November 2015

  2. Oral presentation

    Treatment of leukemia antigen-loss relapses occurring after CD19-targeted immunotherapies by combination of anti-CD123 and anti-CD19 chimeric antigen receptor T cells

    Marco Ruella, David M Barrett, Saad S Kenderian, Olga Shestova, Ted J Hofmann, John Scholler, Simon F Lacey, Jan J Melenhorst, Farzana Nazimuddin, Jessica Perazzelli, David A Christian, Christopher A Hunter, David L Porter, Carl H June, Stephan A Grupp and Saar Gill

    Journal for ImmunoTherapy of Cancer 2015 3(Suppl 2):O5

    Published on: 4 November 2015

  3. Oral presentation

    Interim results of an ongoing Phase I, dose escalation study of MGA271 (Fc-optimized humanized anti-B7-H3 monoclonal antibody) in patients with refractory B7-H3-expressing neoplasms or neoplasms whose vasculature expresses B7-H3

    John Powderly, Gregory Cote, Keith Flaherty, Russell Z Szmulewitz, Antoni Ribas, Jeffrey Weber, Deryk Loo, Jan Baughman, Francine Chen, Paul Moore, Ezio Bonvini, James Vasselli, Jon Wigginton, Roger Cohen, Howard Burris and Bartosz Chmielowski

    Journal for ImmunoTherapy of Cancer 2015 3(Suppl 2):O8

    Published on: 4 November 2015

  4. Oral presentation

    Local immunotherapy with ONCOS-102 shapes harmful tumor associated CD68+ macrophages to become beneficial cells that correlate with increased overall survival

    Sari Pesonen, Johan Lundin, Nina Linder, Riku Turkki, Ari Ristimäki, Timo Joensuu, Kalevi Kairemo, Kaarina Partanen, Tuomo Alanko, Elke Jäger, Julia Karbach, Claudia Wahle, Akseli Hemminki, Charlotta Backman, Mikael von Euler, Tiina Hakonen…

    Journal for ImmunoTherapy of Cancer 2015 3(Suppl 2):O16

    Published on: 4 November 2015

  5. Oral presentation

    Dissecting the tumor micro-environment in triple negative breast cancer identifies a mutually exclusive expression pattern of the immune co-inhibitory molecules B7-H4 and PD-L1

    Donald R Shaffer, Virna Cortez-Retamozo, Kumiko Nagashima, Tong Zi, ChengYi J Shu, Igor Feldman, Veronique Neumeister, Jeff Smith, Mohammad Zafari, Rebecca Larson, Matthew Silver, Robert Mabry, Michael Briskin, Tanya Novobrantseva, David Rimm and Sriram Sathyanarayanan

    Journal for ImmunoTherapy of Cancer 2015 3(Suppl 2):O17

    Published on: 4 November 2015

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