Skip to main content
Figure 3 | Journal for ImmunoTherapy of Cancer

Figure 3

From: Presence of antigen-specific somatic allelic mutations and splice variants do not predict for immunological response to genetic vaccination

Figure 3

Peptides specific to PAP splice variant proteins designed for the detection of pre-existing immune responses span splice junctions of variant proteins. Panel A: Shown is an amino acid sequence alignment of the four protein coding alternative splice variants of PAP with the native PAP protein. Panel B: Shown are the amino acid sequences of five peptide pools spanning the alternative splice variants of PAP, including three pools for the transmembrane domain of ACPP-003.

Back to article page