Skip to main content

Table 3 mRNA transcripts of native and splice variants of PAP are detectable in pre-vaccination patient PBMC

From: Presence of antigen-specific somatic allelic mutations and splice variants do not predict for immunological response to genetic vaccination

   PAP mRNA transcripts    Control mRNA transcripts
  Patients ACPP-001 ACPP-002 ACPP-003 ACPP-004 β-actin KLK3-201
  1 X   X   X X
  2 X X X X X X
  3 X X X X X  
  4 X X X   X X
  5      X X
  6 X X X X X  
Non-Responders 7 X X X   X  
  8 X   X   X X
  10    X   X X
  11 X X X X X X
  12 X   X X X X
  13      X  
  14 X X X   X X
  15 X   X X X X
  16 X   X   X X
  17 X X X X X X
  18 X   X   X X
  19 X X X   X X
  24 X     X X
Immune Responders 25 X     X  
  26      X X
  27 X X X X X X
  28 X   X   X X
  29 X   X X X X
  31 X   X   X X
  32 X   X   X X
  33 X X X X X X
  1. Shown are native and alternative splice variant PAP products detected among immune non-responding patients (top, 1–13) and immune responding patients (bottom, 14–33). Detection of an mRNA transcript is indicated by an X.