Changes in tyrosinase
HLA*A0101-restricted tetramer-reactive CD8+T cells following mouse tyrosinase DNA vaccination. Each point refers to the mean of triplicate values. Most patients also underwent two peripheral blood draws at baseline one week apart prior to receiving vaccination. The values at baseline represent the mean of both of these time-points. * Refers to patients with increase in tetramer-reactive CD8+ cells. (Patient Tyr-9 scored positive for both Tyr tetramers, patient Tyr-26, 27 and Tyr-28 had a single Tyr tetramer positive after vaccination).