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Table 1 Comparison of MST among different groups in three xenograft mouse models

From: Antitumor efficacy of D2C7-(scdsFv)-PE38KDEL, a novel immunotoxin targeting EGFRwt and EGFRvIII, by convection-enhanced delivery in orthotopic brain tumor mouse models

(Day)

Vehicle

P588

D2C7

Log-rank test

43 MST

14

15

43.5*

0.0010

NR6M MST

25

25

32

0.0074

D270MG MST

26

19.5

64**

0.0061

  1. *Last 4 mice were euthanized on Day 90;
  2. **Last 8 mice were euthanized on Day 64.
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