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Table 1 IL-2 responsiveness in peripheral blood T cells before and after DC vaccination

From: Cytokine responsiveness of CD8+ T cells is a reproducible biomarker for the clinical efficacy of dendritic cell vaccination in glioblastoma patients

Patient ID Overall survival (months) Pre-DC Vax CD3+CD8+ EC-50 Post-DC Vax CD3+CD8+ EC-50 Pre-DC Vax CD3+CD4+ EC50 Post-DC Vax CD3+CD4+ EC-50
1-708 33.83 128.2 13.16 3.528 13.39
34-730 16.23 126.2 66.01 20.73 0.005
36-852 >43.9 27.95 0.017 4.407 0.002
6-815 17.3 1.854 0.196 0.002 2.355
19-539 34.9 8.223 14.27 1.386 1.178
GAA-03 35.3 60.52 18.63 29.64 0.003
GAA-05 11.73 38.2 34.69 11.43 5.245
GAA-07 17.2 16.52 6.07 5.446 5.237
GAA-09 11.0 31.19 22.38 7.2 7.7
AVERAGE:   50.70 19.15 9.31 3.90
SEM:   16.90 6.38 3.10 1.30
T-test:   0.045   0.223  
  1. 1The EC-50 for IL-2 responsiveness (pSTAT-5) was calculated in CD3+8+ and CD3+CD4+ peripheral blood T cells after a 20-minute stimulation with increasing dosages of IL-2, FACS analysis, and log transformation.