Figure 5From: Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors Effect of TLR agonists on large established CT26 tumors. 105 CT26 colon cancer cells were implanted into the flank of syngeneic BALB/c mice. When the tumors reached ≈ 800 mm3 in volume they were injected with 200 μg of CpG or control ODN and/or 100 μg of 3M-052 or 3M control twice weekly for one month. The change in tumor volume of 15 mice/group is shown (mean + SE).Back to article page