Figure 6
From: Combination therapy targeting toll like receptors 7, 8 and 9 eliminates large established tumors
Effect of TLR agonists on large established B16-F10 tumors. 105 B16-F10 melanoma cancer cells were implanted into the flank of syngeneic C57Bl/6 mice. When the tumors reached ≈ 500 mm3 in volume they were injected with 200 μg of CpG or control ODN and/or 100 μg of 3M-052 or 3M control twice weekly for one month. The change in tumor volume of 8 mice/group is shown (mean + SE).