Figure 4

The waterfall plot demonstrates the percent change of measurements by two criteria at the first follow-up scan. Dark gray bars represent the percent changes by irRC simulating RECIST1.0, and light gray bars represent the percent changes by irRC simulating RECIST1.1. Dashed lines at +20% and -30% represent the cut-off values for progressive disease and partial response, respectively. 5 patients with discordant assessment are marked with asterisks (*).