Figure 2

Treatment with LBH589 alters the peripheral cytokine milieu of non-tumor bearing mice treated with LBH589. A. Treatment scheme. Asterisks indicate timepoints in which serum was collected. B. Serum levels of cytokines in groups treated with and without LBH589. Serum was taken one day prior to dendritic cell vaccination, and then four hours post vaccination. C. Serum cytokine levels of the same treatment groups taken prior to dendritic cell revaccination on day 7 and then 72 hours following revaccination. Serum from at least 6 mice was measured per cytokine. Student’s t-tests were performed to determine statistical significance between groups.