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Figure 6 | Journal for ImmunoTherapy of Cancer

Figure 6

From: The histone deacetylase inhibitor, LBH589, promotes the systemic cytokine and effector responses of adoptively transferred CD8+ T cells

Figure 6

LBH589 increases expression of markers of T-cell activation and costimulation. Splenocytes from mice treated with and without LBH589 were assayed for the expression of CD25, OX-40, CD40L and ten days after adoptive cell transfer. Representative plots are gated on CD8+ Thy1.1+ Pmel T cells. Each group contained 6 mice with similar data obtained in an independent experiment. Student’s t-tests were performed to determine statistical significance between groups.

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