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Figure 1 | Journal for ImmunoTherapy of Cancer

Figure 1

From: Functional and molecular characterization of single serial killer CAR+ T cells demonstrates adaptive modification of behavior and fate based on tumor cell density

Figure 1

Frequency and kinetics of effector apoptosis are dependent on functional activation by varying numbers of tumor cells. (A) Box and whisker plots (extremities indicate range) of the distribution of single CAR+ T cells undergoing AICD. (B) Donor variation in the average frequencies of apoptotic killer CAR+ T cells. P-values were computed using an unpaired two-tailed t-test.

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