Figure 2
From: Anti-tumor characteristics of radiation-induced tumor-infiltrating neutrophils
Radiation-induced CD11b+Gr1+ cells impact therapeutic response of radiation. RM-9- (A), LLC (B), and 4T1- (C) bearing mice were treated with i.p.injection of anti-Ly6G mAb (▲ and Δ) for neutrophil depletion or Isotype control (° and •) prior to irradiation (• and ▲) and compared to unirradiated (° and Δ) control tumor grafts. The results show a significant decrease in radiation therapeutic response with the depletion of neutrophils.