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Figure 1 | Journal for ImmunoTherapy of Cancer

Figure 1

From: Transcriptional regulation of IFN-λ genes in Hepatitis C virus-infected hepatocytes via IRF-3·IRF-7·NF-κB complex

Figure 1

Hepatic induction of IFN-λ genes during HCV infection. A, B. Total RNA was extracted from liver tissues of healthy and chronic HCV patients for IL-28A/B (A) and IL-29 (B) mRNA quantification by real-time PCR. C-F. Human primary hepatocytes were inoculated with UV-irradiated JFH-1 or JFH-1 for the indicated amounts of time, and IFN-λ gene levels were quantified by real-time PCR (C, E) while protein levels were analyzed by ELISA (D, F). Data represent means ± SD of three independent experiments (p<0.01).

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