Skip to main content

Table 1 Nominal 1-sided P values for ORR and PFS calculated from logistic and Cox regression, respectively, using signature score as a continuous variable.

From: Relationship between immune gene signatures and clinical response to PD-1 blockade with pembrolizumab (MK-3475) in patients with advanced solid tumors

Signature HNSCC Gastric Cancer
  ORR PFS ORR PFS
IFN-λ 0.005 <0.001 0.077 0.032
TCR signaling 0.071 0.002 0.034 0.024
Expanded immune 0.015 <0.001 0.062 0.049
De novo 0.018 <0.001 0.068 0.037