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Table 1 Nominal 1-sided P values for ORR and PFS calculated from logistic and Cox regression, respectively, using signature score as a continuous variable.

From: Relationship between immune gene signatures and clinical response to PD-1 blockade with pembrolizumab (MK-3475) in patients with advanced solid tumors

Signature

HNSCC

Gastric Cancer

 

ORR

PFS

ORR

PFS

IFN-λ

0.005

<0.001

0.077

0.032

TCR signaling

0.071

0.002

0.034

0.024

Expanded immune

0.015

<0.001

0.062

0.049

De novo

0.018

<0.001

0.068

0.037