A logarithmic plot of blood lymphocyte, eosinophil, platelet and granulocyte absolute counts and hemoglobin during a cycle of HD IL-2 administration. Platelet and lymphocyte counts fall rapidly to very low levels. Eosinophils progressively rise during administration. After cessation of treatment, platelets and lymphocytes quickly return to normal and often rebound to 2-5 times their baseline levels. Eosinophilia may persist for weeks.