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Table 1 Expression pattern of the major Fc γRs in human and mouse

From: The role of Fc gamma receptors in the activity of immunomodulatory antibodies for cancer

Cell type

FcγRI

Fc γ RIIb

hFcγRIIa

mFcγRIII

hFcγRIIIa

mFcγRIV

h

m

h

m

B cells

  

+

+

    

DCs

+

+

+

+

+

+

  

NK cells

     

+

+

 

Monocytes/Macrophages

+

~

~

+

+

+

+

+

Neutrophils

(+)

 

~

+

+

+

 

+

  1. Italics indicates an inhibitory receptor. Normal text indicates an activating receptor. Human receptors are denoted by h and mouse receptors by m. + indicates expression, (+) indicates inducible expression and ~ indicates expression on only a sub-set or on cells at specific physiological locations [2],[3].