Figure 5From: MAGE-specific T cells detected directly ex-vivo correlate with complete remission in metastatic breast cancer patients after sequential immune-endocrine therapy Representative analysis of tumor antigen-specific responses in non-responder patient. Representative ex-vivo analysis of antigen-specific CD8+ (A) and CD4+ (B) T cell responses from bulk PBMCs of one of three patients who also received IMQ treatment alongside Patient 1 and 2 by intracellular staining for IFN-γ and TNF-α. As controls, T cells were also stimulated with MOG and CEF overlapping peptides and PMA/Ionomycin.Back to article page