Tetramer guided, cell sorter assisted production of clinical grade autologous NY-ESO-1 specific CD8+ T cells

Table 1 Leukapheresis yield in advanced sarcoma patients

	Sarcoma subtype	Age	Chemotherapy prior to leukapharesis	Sites of disease	Leukapharesis yield (×10^9)	Yield of CD25 depletion (×10^9)
Patient 1	SS	47	None	Soft tissue, lung, brain	7.11	0.99
Patient 2	MRCL	35	Rtx	Bone, soft tissue, lung	6.9	1.44
Patient 3	SS	48	A/I, HD Ifos, Rtx	Brain, lung	5.14	1.2
Patient 4	SS	46	A/I/Vincristine, Rtx/Ifos	Lung	14	1.365
Patient 5	SS	26	None	Lung, kidney, soft tissue	11.2	1.56
Patient 6	SS	42	None	Recurrent, locally advanced axillary disease	13.76	1.46

Rtx - Radiation therapy; A/I - Adriamycin and Ifosfamide; Gem/tax - gemcitabine and docetaxel; Doxil - liposomal doxorubicin; A/I/DTIC - Adriamycin, Ifosfamide and Decarbazine.