Table 5 Percentage distribution of CD4 + T cell phenotypes: summary of CD4 + T cells phenotypes in OVC patients
Mean% cell population (+/- SD) | PBL | Ascitis | TIL | Met |
|---|---|---|---|---|
CD25+ Foxp3+ CD4+ T cells | 4.6 (+/− 3.4) | 10.31 (+/− 4.4) | 19.7 (+/−10.1) | 19.8 (+/− 11.4) |
Ki-67+ Treg cells | 13.9 (+/− 8.2) | 18.2 (+/− 12) | 20.4 (+/−10.2) | 22 (+/−11.3) |
HLA-DR + Treg cells | 37.4 (+/− 17.4) | 47.0 (+/− 14.1) | 74.6 (+/− 12.1) | 75.1 (+/− 8.3) |
HLA-DR + CD4+ T cells | 7.6 (+/− 7.7) | 25.5 (+/− 17.3) | 48 (+/− 20.6) | 42.7 (+/−18.2) |
Helios + Treg cells | 50.7 (+/− 19.8) | 58.7 (+/− 27.1) | 77.2 (+/− 12.6) | 76.3 (+/− 11.0) |
HLA-DR + Helios + Treg cells | 24.1 (+/− 7.7) | 35.1 (+/−15.9) | 59.2 (+/− 14.2) | 62 (+/− 8.7) |
CD39+ Treg cells | 29.1 (+/− 16.7) | 43.1 (+/− 20.9) | 72.2 (+/− 21.1) | 67.5 (+/− 23.7) |
HLA-DR + CD39+ Treg cells | 21.1 (+/− 15) | 28.8 (+/− 15) | 54.4 (+/− 19.3) | 53.4 (+/− 18.1) |
CTLA-4 Treg cells | 50.6 (+/− 27.8) | 63.8 (+/− 28) | 81.6 (+/− 14.9) | 77.1 (+/− 20.2) |
CD39+ CTLA-4+ Treg cells | 18.5 (+/− 17.8) | 27.2 (+/− 14.2) | 61.7 (+/− 20.3) | 53.6 (+/− 23) |