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Table 5 Percentage distribution of CD4 + T cell phenotypes: summary of CD4 + T cells phenotypes in OVC patients

From: Detailed characterization of tumor infiltrating lymphocytes in two distinct human solid malignancies show phenotypic similarities

Mean% cell population (+/- SD) PBL Ascitis TIL Met
CD25+ Foxp3+ CD4+ T cells 4.6 (+/− 3.4) 10.31 (+/− 4.4) 19.7 (+/−10.1) 19.8 (+/− 11.4)
Ki-67+ Treg cells 13.9 (+/− 8.2) 18.2 (+/− 12) 20.4 (+/−10.2) 22 (+/−11.3)
HLA-DR + Treg cells 37.4 (+/− 17.4) 47.0 (+/− 14.1) 74.6 (+/− 12.1) 75.1 (+/− 8.3)
HLA-DR + CD4+ T cells 7.6 (+/− 7.7) 25.5 (+/− 17.3) 48 (+/− 20.6) 42.7 (+/−18.2)
Helios + Treg cells 50.7 (+/− 19.8) 58.7 (+/− 27.1) 77.2 (+/− 12.6) 76.3 (+/− 11.0)
HLA-DR + Helios + Treg cells 24.1 (+/− 7.7) 35.1 (+/−15.9) 59.2 (+/− 14.2) 62 (+/− 8.7)
CD39+ Treg cells 29.1 (+/− 16.7) 43.1 (+/− 20.9) 72.2 (+/− 21.1) 67.5 (+/− 23.7)
HLA-DR + CD39+ Treg cells 21.1 (+/− 15) 28.8 (+/− 15) 54.4 (+/− 19.3) 53.4 (+/− 18.1)
CTLA-4 Treg cells 50.6 (+/− 27.8) 63.8 (+/− 28) 81.6 (+/− 14.9) 77.1 (+/− 20.2)
CD39+ CTLA-4+ Treg cells 18.5 (+/− 17.8) 27.2 (+/− 14.2) 61.7 (+/− 20.3) 53.6 (+/− 23)