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Table 1 Summary of patient characteristics and tumor measurements

From: Response assessment in metastatic melanoma treated with ipilimumab and bevacizumab: CT tumor size and density as markers for response and outcome

Baseline demographics and disease characteristics

Gender

Male

14 (66.7)

Female

7 (33.3)

Age (years)

Median [Range]

53 [25-68]

Tumor stage

IV

20 (95.2)

III Unresectable

1 (4.8)

Doses of agents

Ipi: 10 mg/kg, Bev: 15 mg/kg

8 (38.1)

Ipi: 10 mg/kg, Bev: 7.5 mg/kg

5 (23.8)

Ipi: 3 mg/kg, Bev: 15 mg/kg

2 (9.5)

Ipi: 3 mg/kg, Bev: 7.5 mg/kg

6 (28.6)

Baseline sum diameter (mm)

Median [Range]

38 [10-178]

Mean [SD]

55.1 [43.9]

Baseline average density (HU)

Median [Range]

43.2 [8.0-69.2]

Mean [SD]

43.4 [16.2]

Changes from the baseline measurements

Absolute diameter change at 1 st follow-up (mm)

Median [Range]

0 [-21.0 - 56]

Mean [SD]

5.5 [18.0]

Proportional diameter change at 1 st follow-up (%)

Median [Range]

0 [-64.7 - 85.7]

Mean [SD]

3.6 [34.4]

Absolute density change at 1 st follow-up (HU)

Median [Range]

-4.3 [-24.3 - 18.5]

Mean [SD]

-3.1 [10.8]

Proportional density change at 1 st follow-up (%)

Median [Range]

-8.4 [-44.3 - 49.1]

Mean [SD]

-3.1 [24.5]

  1. The numbers represent the number of patients with percentage in parentheses, unless otherwise specified.
  2. Ipi = ipilimumab, Bev = bevacizumab.