Table 4 Intra- and inter-observer variability of measurements in 21 patients

From: Response assessment in metastatic melanoma treated with ipilimumab and bevacizumab: CT tumor size and density as markers for response and outcome

Intra-observer variability
	CCC [95% CI]	Mean relative difference	95% limits of agreement
Diameter	0.9865 [0.9691 - 0.9941]	-3.5 (%)	-22.5, 15.5 (%)
CT density	0.9967 [0.9921 - 0.9987]	0.3 (%)	-5.8, 6.5 (%)
CT density	0.9967 [0.9921 - 0.9987]	0.2 (HU)	-2.3, 2.7 (HU)
Inter-observer variability
Diameter	0.9774 [0.9459 - 0.9907]	-0.2 (%)	-27.1, 26.7 (%)
CT density	0.9934 [0.9841 - 0.9973]	-1.9 (%)	-12.0, 8.3 (%)
CT density	0.9934 [0.9841 - 0.9973]	-0.6 (HU)	-4.1, 2.8 (HU)

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