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Figure 3 | Journal for ImmunoTherapy of Cancer

Figure 3

From: Combination of IFNα and poly-I:C reprograms bladder cancer microenvironment for enhanced CTL attraction

Figure 3

BCG exposure of bladder tissues does not induce CXCL10, but further enhances tumor production of MDSC/T reg - attracting CCL22 and CXCL8. Bladder tumor biopsies were cultured in the absence or presence of BCG (2 × 106 CFU) for 24 hours. CXCL10, CCL22 and CXCL8 proteins in tumor supernatants were measured by ELISA and expressed as ng/ml. The results were evaluated using two- tailed, paired Student’s t test. Statistically significant differences between groups are highlighted by * (P < 0.05). NS-Not significant.

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