Development of endogenous luc2 specific IgG antibodies did not impact tumor growth.
(A) Serum firefly luciferase specific IgG μg/mL (y-axis) for ID8 luc2 mice, over time in weeks (x-axis). Bars represent mean and SEM. n = 16 (B) Bioluminescent imaging of ID8 Luc2 mice at 4 and 6 weeks post tumor implant. Serum firefly luciferase specific IgG μg/mL (y-axis) compared to matched bioluminescent flux (x-axis). Linear regression line shown in blue. (n = 32).