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Figure 1 | Journal for ImmunoTherapy of Cancer

Figure 1

From: NK cells and CD8+ T cells cooperate to improve therapeutic responses in melanoma treated with interleukin-2 (IL-2) and CTLA-4 blockade

Figure 1

Combination IL-2 and CTLA-4 blockade immunotherapy results in reduced tumor growth and prolonged survival. (A) Schematic of the experimental design. (B) Cumulative graph of mean tumor size (mm2) per group from experiment described in (A). (C) Tumor size (mm2) of individual mice in each group from experiment described in (A). (D) Cumulative graph of mean percent (%) survival per group from experiment described in (A). Seven to ten mice were included in each group. Graphs represent one experiment of six conducted with similar results. *P < 0.05, **P < 0.001, ***P < 0.001, ns = not significant.

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