Ipilimumab Treatment Course of Patient with UC. A. re-staging chest axial PET CT imaging of patient at different time points. (1) prior to initial dose of ipilimumab, (2) following first dose of ipilimumab and ipilimumab-induced grade III colitis, (3) following total colectomy and prior to re-treatment with ipilimumab, (4) complete disease resolution following a four-dose regimen of ipilimumab. B. Time line of clinical events.