Skip to main content
Figure 3 | Journal for ImmunoTherapy of Cancer

Figure 3

From: Combination immunotherapy with α-CTLA-4 and α-PD-L1 antibody blockade prevents immune escape and leads to complete control of metastatic osteosarcoma

Figure 3

Dual α-CTLA-4/α-PD-L1 mAb treatment can completely eradicate metastatic osteosarcoma. Survival of combinational treatment of implantable metastatic osteosarcoma with α-CTLA-4 and α-PD-L1 mAb was significantly higher than α-PD-L1 mAb treatment alone, p = 0.0177. Additionally, survival of combination treatment α-CTLA-4/α-PD-L1 mAb compared to α-CTLA-4 mAb treatment alone was significantly different with a p value of p < 0.0001. α-CTLA-4 mAb alone was not significantly different than mock treated mice. N = 10 for all treatment groups.

Back to article page