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Table 1 Baseline characteristics of the patient population (N = 44)

From: Self-adjuvanted mRNA vaccination in advanced prostate cancer patients: a first-in-man phase I/IIa study

Characteristic

Total (N = 44)

Age, years

 

 Median

67

 Range

51–84

Gleason score available, n (%)

39 (89)

 ≤7

15 (38)

 >7

24 (62)

PSA level at baseline, ng/mL

 

 Median

22.2

 Range

0.2–746

Extent of disease, n (%)

 

 Local relapse

6 (14)

 Locoregional

1 (2)

 Metastases total

36 (84)

 Peritoneum

1 (2)

 Pelvis

1 (2)

 Bladder

1 (2)

 Lung

3 (7)

 Liver

1 (2)

 Lymph nodes

26 (59)

 Bone

28 (64)

ECOG, n (%)

 

 0

43 (98)

 1

1 (2)

Time since diagnosis, weeks

 

 Mean

280.4

 SD

228.15

Previous therapy, n (%)

 

 Prostatectomy

23 (52)

 Radiotherapy

28 (64)

 Hormone ablation

44 (100)

  1. ECOG, Eastern Cooperative Oncology Group; PSA, prostate-specific antigen; SD, standard deviation