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Fig. 4 | Journal for Immunotherapy of Cancer

Fig. 4

From: Enhancing the discovery and development of immunotherapies for cancer using quantitative and systems pharmacology: Interleukin-12 as a case study

Fig. 4

WISP1 is upregulated in tumor tissue samples obtained from patients with invasive breast cancer. The histograms for WISP1 (a) and SPARC (b) gene expression assayed in homogenized tissue samples from invasive breast tumors (n = 520, red curves) and matched normal breast tissues (n = 61, black curves). Gene expression data were obtained from the invasive breast cancer arm of The Cancer Genome Atlas (TCGA) [116]

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