Fig. 3
From: Characterization of the human T cell response to in vitro CD27 costimulation with varlilumab
Pathways differentially affected by varlilumab costimulation. A bar chart showing the frequency of representative categories within the gene list (Varlilumab/Test versus Control/Iso/ hIgG_Stringent DGA) with functional grouping. Size of bars denotes the number of genes/targets populating the pathway and independent of the importance of any pathway relative to other pathways. Data were curated on Miltenyi-Biotec’s database of annotated and enriched pathway targets. Numbers in parenthesis refer to number of genes/targets either induced (upregulated) or repressed (downregulated) in the pathway(s) relative to control. DGA, Differential Gene Expression Analysis