Table 1 Patient (n = 16) and radiation treatment (n = 51) characteristics
From: Ipilmumab and cranial radiation in metastatic melanoma patients: a case series and review
Patients | |
|---|---|
Male sex | 13 (81 %) |
Age at time of initial brain radiation, median (range) | 57 years (40 – 85 years) |
Ipilimumab dosing | |
10 mg/kg | 2 (13 %) |
3 mg/kg | 14 (88 %) |
Number of ipilimumab treatments, median (range) | 4 (1 – 17) |
Radiation Treatment | |
Number of radiation courses per patient, median (range) | 3 (1–8) |
Number of lesions irradiated | |
1 | 23 (45 %) |
2-3 | 15 (29 %) |
>3 | 13 (25 %) |
Type of radiotherapya | |
Whole brain radiation | 5 (10 %) |
Stereotactic Radiosurgery | 46 (90 %) |
Radiation Dose (Gray), median (range) | |
Whole brain radiation | 36 Gy (20 – 36 Gy) |
Stereotactic Radiosurgeryb | 22 Gy (18 – 24 Gy) |
Location of index lesion | |
Skin/subcutaneous tissue/lymph nodes | 8 (26 %) |
Lung | 14 (45 %) |
Other | 9 (29 %) |
None | 3 |
Not imaged / Unknown | 17 |