Skip to main content

Table 1 Patient (n = 16) and radiation treatment (n = 51) characteristics

From: Ipilmumab and cranial radiation in metastatic melanoma patients: a case series and review

Patients
Male sex 13 (81 %)
Age at time of initial brain radiation, median (range) 57 years (40 – 85 years)
Ipilimumab dosing  
 10 mg/kg 2 (13 %)
 3 mg/kg 14 (88 %)
Number of ipilimumab treatments, median (range) 4 (1 – 17)
Radiation Treatment
 Number of radiation courses per patient, median (range) 3 (1–8)
Number of lesions irradiated  
 1 23 (45 %)
 2-3 15 (29 %)
 >3 13 (25 %)
Type of radiotherapya  
 Whole brain radiation 5 (10 %)
 Stereotactic Radiosurgery 46 (90 %)
Radiation Dose (Gray), median (range)  
 Whole brain radiation 36 Gy (20 – 36 Gy)
 Stereotactic Radiosurgeryb 22 Gy (18 – 24 Gy)
Location of index lesion  
 Skin/subcutaneous tissue/lymph nodes 8 (26 %)
 Lung 14 (45 %)
 Other 9 (29 %)
 None 3
 Not imaged / Unknown 17
  1. Abbreviations: Gy Gray
  2. aWhole brain treatment given in 2 Gy fractions. Stereotactic radiosurgery treatments were administered in 1–5 fractions
  3. bIf multiple lesions were irradiated to different doses, the mean dose was used for tabulation