Fig. 3

Ang1 and Ang2 inhibitors did not affect tumor-cell number or viability. Human ovarian cancer cells (OV17-1; a), breast cancer cells (MDA-MB-231; b) and prostate cancer cells (LNCaP; c) were treated with the Cmax of mL4-3 and L1-7(N) (16 and 10 μg/mL, respectively) or control (human IgG1-Fc, 26 μg/mL) for 3 days. Cells were then harvested, counted, and assessed for viability via trypan blue exclusion. Cell number is reported as a percentage of untreated cells. Data were analyzed with an unpaired t test. p values are indicated