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Table 1 Amino acid sequences of CAR domains. The ten n-terminal and ten c-terminal amino acids which flank the protein regions utilized as CAR domains (with the exception of c-myc for which the sequence is listed in its entirety)

From: Designed ankyrin repeat proteins are effective targeting elements for chimeric antigen receptors

Murine CAR sequences:   
Domain N-terminus C-terminus
 c-myc tag EQKLISEEDL  
 CD8 hinge VISNSVMYFS SVKGTGLDFA
 CD28 transmembrane and cytoplasmic ALVVVAGVLF PARDFAAYRP
 CD3ζ cytoplasmic LRAKFSRSAE ALHMQTLAPR
Human CAR sequences:   
Domain N-terminus C-terminus
 CD8 hinge SALSNSIMYF GGAVHTRGLD
 CD28 transmembrane and cytoplasmic FWVLVVVGGV PPRDFAAYRS
 CD3ζ cytoplasmic RVKFSRSADA ALHMQALPPR