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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: Systemic inflammation in a melanoma patient treated with immune checkpoint inhibitors—an autopsy study

Fig. 3

Lung damage patterns. a CT Thorax: Pulmonary metastasis before therapy with Ipilimumab (02/2015) b CT Thorax: pulmonary metastasis regression, ground glass opacities after Ipilimumab (04/2015) c sarcoid-like reaction d elastica stain showing epithelioid granulomas surrounded by fibrotic rings e CD8-positive T-cell infiltrates surrounding giant cell granulomas as detected by immunohistochemistry f diffuse alveolar damage; scale bars as indicated

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