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Table 1 Immunoprognostic and Immunotherapeutic Areas

From: Immunodynamics: a cancer immunotherapy trials network review of immune monitoring in immuno-oncology clinical trials

Prognostic

 

 Immunoscore

 

Therapeutic

 

 Conventional Therapies

 

  Chemotherapy

 

  Radiation therapy

 

 ITAs - Passive

 

  Cellular Therapy

 

   Adoptive T and NK cells

 

   CAR T cells

 

 ITAs - Active & Specific

 

   Monoclonal Antibodies

 

   Tumor-targeting

 

   Immune-targeting, including checkpoint inhibitors

 

   Vaccines

 

   In situ Vaccines

 

   Cell-based Vaccines

 

   Dendritic cell–based Vaccines

 

   Non–cell-based Vaccines

 

 ITAs - Active & Nonspecific

 

  Cytokines

 

  IDO Inhibitors

 
  1. CAR chimeric antigen receptor, ITA immune-targeted agent, IDO indoleamine-2,3-dioxygenase