Fig. 4

a PET CT images of the mediastinal mass, pulmonary lesion and renal mass. Left column: Pre- pembrolizumab; right column: 8 weeks after administration of one dose of pembrolizumab. There is near complete involution of the anterior mediastinal mass and a decrease in size of the pulmonary lesion. The size of the renal mass is unchanged. b Size (cm) on axial imaging (CT or PET/CT) of renal, mediastinal and dominant right pulmonary nodule over time. The last scan showed two new subcentimter pulmonary metastases and increased size of a soft tissue component of the left renal mass