Table 1 Subject characteristics

Total study subjects

17

Age, median (Range), years

63

48–81

Sex

Male

14

82 %

Female

3

18 %

ECOG PS pretreatment

0

8

47 %

1

9

53 %

Melanoma Sub-Type

Cutaneous

15

88 %

Mucosal

2

3 %

Prior lines of therapy, n (%)

0

3

18 %

1

4

24 %

2

4

24 %

≥3

6

35 %

Median prior lines of therapy (% pretreated)

2

83 %

Prior Interleukin-2

5

29 %

Prior Ipilimumab

4

24 %

Number of metastatic sites

1

6

35 %

2

4

24 %

≥3

7

41 %

M1a

1

6 %

M1b

5

29 %

M1c

11

65 %