Table 1 Patient demographics and baseline disease characteristics (N = 18 patients)

Age, years; median (range)

53 (30–73)

Cutaneous primary

17 (94)

Unknown primary

1 (6)

Gender

 Female

12 (67)

 Male

6 (33)

Performance status (ECOG)^a

 0

11 (61)

 1

7 (39)

Recurrent disease after prior surgery

15 (83)

Prior adjuvant HDI^b

6 (33)

Presence of in-transit metastases

12 (67)

Estimated risk stage

 IIIB

2 (11)

 IIIC

16 (89)

Tumor mutational status

 BRAF^V600

9 (50)

 NRAS^Q61

5 (28)

 Unknown

1 (5)