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Fig. 3 | Journal for ImmunoTherapy of Cancer

Fig. 3

From: A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma

Fig. 3

Effect of hypofraction on immune cells in patient blood. a Absolute numbers of i) CD3+, ii) CD8+, iii) CD4+ and iv) SSCintCD14+ monocytes by flow cytometry of fresh peripheral blood in patients on a conventionally fractionated regimen (Fract, open symbols) versus a hypofractionated regimen (Hypo, closed symbols). The samples immediately pre-RT and immediately post-RT are highlighted on the first graph. b comparison of absolute numbers of i) CD3+, ii) CD8+, iii) CD4+ and iv) SSCintCD14+ monocytes by flow cytometry of fresh peripheral blood immediately following completion of radiation therapy in patients on a conventionally fractionated regimen (Fract, open symbols) versus a hypofractionated regimen (Hypo, closed symbols). c Analysis of the proportions of i) CD4 and ii) CD8 subpopulations in PBMC collected pretreatment (open circles) and post-treatment with a hypofractionated regimen (closed circles)

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