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Fig. 5 | Journal for ImmunoTherapy of Cancer

Fig. 5

From: A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma

Fig. 5

Link between planning target volume (PTV), spleen dose and T cell count. a) i) Graph showing the PTV for patients receiving a conventionally fractionated regimen (Fract) versus a hypofractionated regimen (Hypo). A subset of patients receiving a conventionally fractionated regimen exhibited a PTV greater than 400 (square symbols). ii) Post-chemoRT blood T cell counts are shown for patients with PTV greater than or less than 400 receiving a fractionated regimen (Fract) versus a hypofractionated regimen (Hypo). b) Relationship between mean spleen dose (Gy) and post-chemoRT blood T cell counts for patients receiving a hypofractionated regimen. Each symbol represents one patient. Key: NS – not significant. ** p < 0.01

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