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Fig. 2 | Journal for ImmunoTherapy of Cancer

Fig. 2

From: Adenosine-generating ovarian cancer cells attract myeloid cells which differentiate into adenosine-generating tumor associated macrophages – a self-amplifying, CD39- and CD73-dependent mechanism for tumor immune escape

Fig. 2

Ectonucleotidases CD39 and CD73 are expressed on CD14+ cells from OvCA ascites. Primary CD14+ cells (TAM) were isolated from OvCA ascites via magnetic cell sorting (n = 9). For control purposes, macrophages and monocytes from healthy donors (n = 8) and peritoneal macrophages from patients with benign disease (n = 8) were obtained and analyzed. For statistical comparison, unpaired two-sided Student’s t test was used

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