Fig. 1

Clinical photographs prior to and during treatment with immune checkpoint inhibition. Panel a shows a photograph of the chest from 10/5/15 prior to initiation of pembrolizumab, with numerous hyperpigmented papules and plaques scattered across the chest. Panel b shows a photograph of the chest from 2/23/16, after completing ipilimumab/nivolumab induction. There is increased confluence of existing lesions, as well as new hyperpigmented papules on the bilateral upper arms and the neck