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Fig. 1 | Journal for ImmunoTherapy of Cancer

Fig. 1

From: Expansion of tumor-infiltrating lymphocytes (TIL) from human pancreatic tumors

Fig. 1

Characterization of pancreatic TIL after expansion. a Expanded pancreatic TIL were characterized phenotypically by flow cytometry for CD4 and CD8 expression on CD3+ lymphocytes (mean % ± SD). n = 19 (b) TIL were surface stained with CD3, CD4, CD8, and CD25, then further characterized by intracellular staining with Foxp3. Data are reported as mean % ± SD. p < 0.0001 as determined by Wilcoxon matched pairs signed rank test. n = 19. c TIL were additionally surface stained for markers of activation and antigen experience CD69 (i, n = 17), CD27 (ii, n = 11), CD28 (iii, n = 11), GITR (iv, n = 8), 4-1BB (v, n = 18), and CD25 (vi, n = 19) on CD4+ and CD8+ cells within the CD3+ lymphocyte population. Summary data are reported as mean % ± SD

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