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Fig. 6 | Journal for ImmunoTherapy of Cancer

Fig. 6

From: Expansion of tumor-infiltrating lymphocytes (TIL) from human pancreatic tumors

Fig. 6

Pancreatic TIL produced tumor specific immune response. CD8-enriched post-REP TIL from two patients were cultured with HLA-matched (in black) or mismatched (in gray) pancreatic cancer cell lines at a 1:1 ratio. a The patient was HLA-A typed as A01/24 and matched with the MiaPaca-2 (A24) cell line, and mismatched with the Panc-1 (A02/11) pancreatic tumor cell lines. b The patient was HLA-A typed as A02/24 and matched with the CFPAC-1 (A02/03) and Panc-1 (A02/11) pancreatic tumor cell lines, and mismatched with HPAFII (A01/11) tumor cell line. IFN-gamma levels in supernatants were measured after 48 h and reported as mean ± SEM and statistical significance was determined by the student’s t-test. *, p < 0.05, **, p < 0.01, ***, p < 0.001

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